Are we living in a simulation?

Since I was a kid I have been wondering:

Are we living in a simulation?

Interestingly, other people have recently picked up on this:

http://www.bbc.com/earth/story/20160901-we-might-live-in-a-computer-program-but-it-may-not-matter

Apart from some strange things in physics (which of course may be better explained in the future by an improved model) are there other things that could indicate that we are in fact living in a simulation?

If the guys running the simulation have some ethical standards (perhaps they even had to submit their simulation experiment to an ethics commitee/IRB: https://en.wikipedia.org/wiki/Institutional_review_board); and if so, what could we potentially assume they would say about termination of simulated beings?

This brings me to the very interesting topic of near-death-experience; people who have had such experiences say they often see a “bright light” they feel like they are in heaven, etc. Animal research has demonstrated that when rats are killed enourmous amounts of chemical substances are released in the brain, that stimulates a feeling of “happiness”; (e.g. same substances that are released when having sex). Also it is interesting to notice that when oxygen flow to the brain stops, the brain stops the heart!

Why is this? What is the evolutionary explanation for all of this? I am not able to spot one — however if we live in a simulation and if the beings that are running it have a certain ethical standard you would expect them to make sure that when concious parts of the simulation is terminated they will be terminated without too much pain and anguish.

So, what do people think? Do the near-death experiences support the we-live-in-a-simulation hypothesis?

(Written after a few beers, hopefully not influencing the punctiation or the logic of this post too much)