Well given enough time and money anything is possible, but there may still be few customers. Being older in concept the ju52 is a less aerodynamically efficient airframe than the dc3 so unless they want to ditch many of the fundamental features that make it characteristically a ju52, except maybe the tri motor layout, then your potential customer has to be happier buying something that has inferior performance to a DC3. 

As for the new unproven engines: all that needs to be said is contained in AVwebs Paul Bertorellis excellent presentation on why new aircraft engine ideas rarely succeed:

https://m.youtube.com/watch?v=_k1TQGK3mZI