Sure im half way through building a replica Airbus A320 Flight Deck. Wannabe and MarkL can vouch for this 🙂 Panels from http://www.flightdecksolutions.com and software from http://www.projectmagenta.com

A 3 screen setup or more is possible. I use 3 monitors/projectors in my Flight Deck and sometimes on FS PC. If anyone wants to see my setup for monitors come along on 19th september to the show @: http://www.pcpilotsireland.com

Or come and see my Flight Deck at http://www.fs-show.com and my Matrox Graphics card!