It’s usually the width of the runways and the taxiways that’s the problem.. due to the extra large wing span and the outer starboard and port engines ingesting debris..if the AN-225 can land and take off from any of these ports ..i think the A380 could do likewise
The AN-225 is operated under special regulations. If it can operate from their, it does not mean that commercial operations are feasible with aircraft of nearly similar size.