Most impossible real passenger flight

Which real passenger flight is thought to be the most impossible to repeat on FS?

I have heard that there was a DC-10 which lost all hydraulic power and all controls because one engine exploded. It was flown solely by throttles of the two remaining engines almost to landing.

Allegedly, no one has ever got that far on FS – everyone falls off the sky mid-air.

For comparison, it has been said that the Concorde crash flight lands safely about once in ten tries in FS.

Is it really a valid comparison?

And is there some other flight that really occurred with passengers and which is even less possible to repeat?