Why not? Didnt Greece Airway do it a few years back and I belive loads were quite good. It is a little far but then again so is TFS etc. They could possibly operate it as a night flight but that creates new problems which Jet2 would have to get sorted.
I wish DUB could get a decent ATH service going as its terrible that we dont Im sure it would make money. MA operated a night flight during the summer with resonable loads nothing fantastic but had to stop as it was causing awful delays to their DUB-BUD in the morning.